Ephedrine → HCID 131716467, compound

HRID 2165591Notes

Reaction equation

HRID 2165591 reaction equation
[Cl:1][C:2]1[CH:27]=[CH:26][C:5]([CH2:6][N:7]2[C:19]3[CH:18]([CH2:20][C:21]([OH:23])=[O:22])[CH2:17][CH2:16][CH2:15][C:14]=3[C:13]3[C:8]2=[C:9]([F:25])[CH:10]=[C:11]([F:24])[CH:12]=3)=[CH:4][CH:3]=1.[CH3:28][C@H](NC)[C@H](O)C1C=CC=CC=1>>[Cl:1][C:2]1[CH:27]=[CH:26][C:5]([CH2:6][N:7]2[C:19]3[CH:18]([CH2:20][C:21]([O:23][CH3:28])=[O:22])[CH2:17][CH2:16][CH2:15][C:14]=3[C:13]3[C:8]2=[C:9]([F:25])[CH:10]=[C:11]([F:24])[CH:12]=3)=[CH:4][CH:3]=1

Participants

3

Reactant 2

HCID 9294EphedrineHCID 14372497HCID 14372497, compound

Product 1

HCID 131716467HCID 131716467, compound

Procedure

Following the method of Example 18, Step II to Step IV, but using 9-p-chlorobenzyl-6,8-difluoro-1,2,3,4-tetrahydrocarbazol-1-yl-acetic acid from Example 30, Step III and using 1(-)ephedrine in Step III, there is obtained the title compound.

Sources & evidence

ORD record
ord-f597e9c3e7d94a918051ef1612807a4d
Source dataset
uspto-grants-1990_07
Patent number
US04940719

Reaction notes

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