Ephedrine → HCID 70431316, compound

HRID 2165592Notes

Reaction equation

[Cl:1][C:2]1[CH:28]=[CH:27][C:5]([CH2:6][N:7]2[C:19]3[CH:18]([CH2:20][C:21]([O:23][CH2:24]C)=[O:22])[CH2:17][CH2:16][CH2:15][C:14]=3[C:13]3[C:8]2=[C:9]([CH3:26])[CH:10]=[CH:11][CH:12]=3)=[CH:4][CH:3]=1.C[C@H](NC)[C@H](O)C1C=CC=CC=1>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([CH2:6][N:7]2[C:19]3[CH:18]([CH2:20][C:21]([O:23][CH3:24])=[O:22])[CH2:17][CH2:16][CH2:15][C:14]=3[C:13]3[C:8]2=[C:9]([CH3:26])[CH:10]=[CH:11][CH:12]=3)=[CH:27][CH:28]=1

Participants

Reactant 2

HCID 9294Ephedrine

HCID 23043082HCID 23043082, compound

Product 1

HCID 70431316HCID 70431316, compound

Procedure

Following the method of Example 18, but using ethyl ester from Example 11 in Step I and using 1(-)ephedrine in Step II, there is obtained the title compound.

Sources & evidence

ORD record: ord-07df17890e2a4885978c3f5901fb9453
Source dataset: uspto-grants-1990_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04940719

Reaction notes

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