HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 14839371, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 483169 | — |
| Reactant | 2-(Thiophen-3-yl)piperazine | HCID 16740794 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 14839371 | HCID 14839371 | 27.5% |
Reaction Steps
A mixture of 1 g of 2-(3-thienyl)piperazine and 538 mg of 7-chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid in 8 ml of pyridine was further reacted as described in Example 26 giving 220 mg of the desired product, mp 198°-200° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04940710 |
| Source dataset | uspto-grants-1990_07 |
| ORD ID | ord-141ffa2a27224bf6a408ccb8997a6d72 |
| Source note | uspto-grants-1990_07 |