HuagongsheHuagongshe Chemistry Print Report · For research reference only
7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid → HCID 14839373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 7-Chloro-1-ethyl-6-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylic acid | HCID 483169 | — |
| Reactant | HCID 19763546 | HCID 19763546 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 14839373 | HCID 14839373 | 18.4% |
Reaction Steps
A mixture of 2.424 g of 2-(5-chloro-2-thienyl)piperazine and 1.076 g of 7-chloro-1-ethyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid in 12 ml of pyridine was refluxed under argon for 24 hours and then cooled. The solid was collected, washed with methanol and ether, then dried giving 320 mg of the desired product, mp 232°-234° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04940710 |
| Source dataset | uspto-grants-1990_07 |
| ORD ID | ord-d70eaa84f75f4591b11c398df4c9ad5e |
| Source note | uspto-grants-1990_07 |