Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Selenium Dioxide | HCID 24007 | — |
| Reactant | 1,4-Dioxane | HCID 31275 | — |
| Reactant | HCID 19763544 | HCID 19763544 | — |
| Product | HCID 19763549 | HCID 19763549 | — |
Reaction Steps
A 31.4 g portion of selenium dioxide was added to a solution of 75 ml of dioxane and 10 ml of water and warmed to 60° C. with stirring. A 50 g portion of 2-acetyl-2,5-dichlorothiophene was added and the mixture was stirred at reflux for 7 hours. The mixture was diluted with dioxane, filtered and evaporated to dryness. Ether was added, then heptane and the mixture refrigerated. The solid was collected, giving 30.1 g of 2,5-dichloro-α-oxo-3-thiopheneacetaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04940710 |
|---|
| Source dataset | uspto-grants-1990_07 |
|---|
| ORD ID | ord-97d1d65d0bbe41618c155df7ce389f5a |
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| Source note | uspto-grants-1990_07 |
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