HRID2165665

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：O=C(O)c1cn(-c2ccc(F)cc2)c2cc(Cl)c(F)cc2c1=O

HCID57338

7-Chloro-6-fluoro-1-(4-fluorophenyl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid

C16H8ClF2NO3

HCID19763604

未命名化合物

PRODUCTS

生成物

结构：O=C(O)c1cn(-c2ccc(F)cc2)c2cc(N3CCNC(COc4ccccc4)C3)c(F)cc2c1=O

HCID14839408

未命名化合物

收率 33.6%

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID1049

Pyridine

C5H5N

PROCEDURE

实验过程

A mixture of 0.6 g of 7-chloro-6-fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 1.03 g of 3-(phenoxymethyl)piperazine and 5 ml of pyridine was reacted as described in Example 81, giving 295 mg of the desired product, mp 204°-207° C.

WORKUP

后处理

customwas reacted