HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2165675Generated: November 1, 2026
Fluoroquinolonic acid → HCID 14839412, compound
https://huagongshe.com/reaction/2165675
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Fluoroquinolonic acid | HCID 483180 | — |
| Reactant | 2-Cyclopropylpiperazine | HCID 19763540 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 14839412 | HCID 14839412 | 17.5% |
Reaction Steps
A mixture of 787 mg of 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 1.736 g of 3-cyclopropylpiperazine and 8 ml of pyridine was heated at 140° C. in a pressure bottle for 18 hours and then purified as described in Example 95, giving 182 mg of the desired product, mp 245° C. (dec.).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04940710 |
|---|
| Source dataset | uspto-grants-1990_07 |
|---|
| ORD ID | ord-7f1dca08ec9a4688851d1381477d7471 |
|---|
| Source note | uspto-grants-1990_07 |
|---|
