HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 2165682Generated: October 31, 2026
Fluoroquinolonic acid → HCID 19763613, compound
https://huagongshe.com/reaction/2165682
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Fluoroquinolonic acid | HCID 483180 | — |
| Reactant | HCID 19763589 | HCID 19763589 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 19763613 | HCID 19763613 | 13.5% |
Reaction Steps
A mixture of 1.23 g of 7-chloro-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acid, 1.95 g of 3-ethynylpiperazine and 15 ml of pyridine is heated at 140° C. in a pressure bottle for 18 hours and then purified as described in Example 101, giving 210 mg of the desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04940710 |
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| Source dataset | uspto-grants-1990_07 |
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| ORD ID | ord-bc4757aa280347819b5727ffedb018e0 |
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| Source note | uspto-grants-1990_07 |
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