Triethylamine → HCID 23043003, compound

Participants

Reaction Steps

In a manner similar to that of Example 1, the title compound was prepared from 4.71 g (12 mmol) of 4,6-dimethyl-5-hydroxy-2-phenylhexylaminopyrimidine phosphate salt, triethylamine (16.52 ml, 120 mmol) and ethyl chloroformate (1.7 ml, 18 mmol) to afford 3.8 g of product, mp: 44°-45° C. Mass spectrum m/e=371. NMR (CDCl3) delta: 7.34-7.16 (m, 5H): 5.00 (bs, 1H); 4.36 (q, 6, 3 Hz, 2H): 3.40 (q, 6, 3 Hz, 2H): 2.65, (t, 3 Hz, 2H); 1.74-1.36) (m, 11H). IR (CHCl3): 1761, 1583 cm-1. Anal. Calc'd for C21H29N3O3 : C, 67.90 H, 7.87; N, 11.31. Found: C, 67.95; H, 7.85; N, 11.14.

Provenance & Evidence