Chloride → HCID 86744100, compound

Participants

Reaction Steps

In a manner similar to (i), erucic acid (1 g) was converted to its chloride, to which was added 2-(4-pyridinyl)-4-thiazolidine carboxylic acid (618 mg). The mixture was stirred in pyridine (6 ml)-methylene chloride (2 ml) at room temperature for two hours. The solvent was concentrated, then the residue was washed with water. Resultant precipitates were dried and purified by means of a silica gel column chromatography (chloroform:methanol=10:1), followed by recrystallization from methanol to afford colorless crystals [1.58 g (yield 99%)], m.p. 156 to 158° C.

Provenance & Evidence