HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thiodiglycol → 1-(4-Chlorophenyl)-4,4-dimethyl-3-pentanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thiodiglycol | HCID 5447 | — |
| Reactant | 5-(4-Chlorophenyl)-2,2-dimethylpent-4-en-3-one | HCID 306049 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | 1-(4-Chlorophenyl)-4,4-dimethyl-3-pentanone | HCID 94617 | — |
Reaction Steps
Hydrogenation of 139 g of 5-(4-chlorophenyl)-2,2-dimethylpent-4-en-3-one in 245 g of methanol or toluene at 100° C. on 5.6 g of Raney nickel with and without addition of bis-(2-hydroxyethyl) sulphide to give 5-(4-chlorophenyl)- 2,2-dimethylpentan-3-one (final product).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04940819 |
| Source dataset | uspto-grants-1990_07 |
| ORD ID | ord-aa64cf4791fb44259148b642ed933f2a |
| Source note | uspto-grants-1990_07 |