HCID 17990189, compound → HCID 23042371, compound

HRID 2165795Notes

Reaction equation

HRID 2165795 reaction equation
ClC1C=C(F)C(N2C(=O)C=C(C)N(C(F)F)C2=O)=CC=1C(O)=O.[Cl:24][C:25]1[CH:36]=[C:35]([F:37])[C:34]([N:38]2[C:43](=[O:44])[C:42](C)=[C:41]([CH3:46])[N:40]([CH:47]([F:49])[F:48])[C:39]2=[O:50])=[CH:33][C:26]=1[C:27]([O:29][CH:30](C)C)=[O:28].ClC1C=C(F)C(N2C(=O)C(F)=C(C)N(C(F)F)C2=O)=CC=1C(OC(C)C)=O.ClC1C=CC(N2C(=O)C=C(C)N(C(F)F)C2=O)=CC=1C(OC(C)C)=O.ClC1C=C(F)C(N2C(=O)C=C(C)N(C(F)(F)C(F)F)C2=O)=CC=1C(OC(C)C)=O>>[Cl:24][C:25]1[CH:36]=[C:35]([F:37])[C:34]([N:38]2[C:43](=[O:44])[CH:42]=[C:41]([CH3:46])[N:40]([CH:47]([F:48])[F:49])[C:39]2=[O:50])=[CH:33][C:26]=1[C:27]([O:29][CH3:30])=[O:28]

Participants

6

Reactant 5

HCID 17990189HCID 17990189, compoundHCID 23042370HCID 23042370, compoundHCID 23042382HCID 23042382, compoundHCID 23042386HCID 23042386, compoundHCID 23042391HCID 23042391, compound

Product 1

HCID 23042371HCID 23042371, compound

Procedure

Further representatives of such compounds of formula I are the ethyl, n-propyl, n-butyl, n-hexyl n-octyl, sec.-butyl, 1-methylbutyl, neopentyl, isobutyl, isopentyl, 2-methylbutyl, 1,2-dimethylpropyl, tert.butyl, 1-ethylpropyl, allyl, 2-butenyl, 3-methyl-2-butenyl, 3-methyl-3-butenyl 1-ethyl-2-propenyl, 4-pentenyl, 1-methyl-2-butenyl, 1-methyl-3-butenyl, 3-butenyl, 2-methyl-2-propenyl, 3-butynyl, 2-butynyl, methoxymethyl, ethoxymethyl, n-propoxymethyl, isopropoxymethyl, n-pentyloxymethyl, 1-methoxyethyl, 2-methoxyethyl 2-ethoxyethyl, 2-isopropoxyethyl, 2-methoxy-1-methylethyl, 2-n-butyloxyethyl, cyclopentyl, cyclohexyl, cycloheptyl, cyclopropylmethyl, 1-cyclopropylethyl, 3-tetrahydrofuryl, tetrahydrofurfuryl, 1,3-dioxan-5-yl, 1,3-dioxolan-5-ylmethyl, benzyl and 4-methoxyphenyl esters of 2-chloro-5-[3-difluoromethyl-3,6-dihydro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-4-fluorobenzoic acid, isopropyl 2-chloro-5-[3-difluoromethyl-3,6-dihydro-4,5-dimethyl-2,6-dioxo-1(2H)-pyrimidinyl]-4-fluorobenzoate, isopropyl 2-chloro-5-[3-difluoromethyl-3,6-dihydro-5-fluoro-4-methyl-2,6-dioxo-1(2H)-pyrimidinyl]-4-fluorobenzoate, isopropyl 2-chloro-5-[3-difluoromethyl-3,6-dihydro-4-methyl-2 6-dioxo-1(2H)-pyrimidinyl]-benzoate and isopropyl 2-chloro-5-[3,6-dihydro-4-methyl-3-(1,1,2,2-tetrafluoroethyl)-2,6-dioxo-1(2H)-pyrimidinyl]-4-fluorobenzoate.

Sources & evidence

ORD record
ord-45e5407fedb04e9fa50a54cf9404974e
Source dataset
uspto-grants-1990_07
Patent number
US04941909

Reaction notes

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