Water → 4-chloro-N-hexadecyl-N-methyl-3-nitrobenzenesulfonamide

Participants

Reaction Steps

170 g of 4-chloro-3-nitro-N-hexadecylbenzenesulfonamide was dissolved in 640 ml of acetone, and 79 g of potassium carbonate, 4006 ml of polyethylene glycol and 71 g of dimethylsulfuric acid were then added thereto and heated under reflux for 5 hours. 240 ml of acetone was added thereto, 870 ml of water was added dropwise at 40° C., and the whole was cooled to room temperature, whereby a crystal precipitated out. The crystal was taken out by filtration, washed with water and methanol, and dried. Yield: 169 g, 97%.

Provenance & Evidence