3-Methyl-7-propylpurine-2,6-dione → HCID 14851753, compound

HRID 2165819Notes

Reaction equation

HRID 2165819 reaction equation
[CH3:1][N:2]1[C:10]2[N:9]=[CH:8][N:7]([CH2:11][CH2:12][CH3:13])[C:6]=2[C:5](=[O:14])[NH:4][C:3]1=[O:15].[Cl:16][C:17]1[CH:30]=[CH:29][C:20]([O:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27]Br)=[CH:19][CH:18]=1>>[Cl:16][C:17]1[CH:30]=[CH:29][C:20]([O:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][N:4]2[C:5](=[O:14])[C:6]3[N:7]([CH2:11][CH2:12][CH3:13])[CH:8]=[N:9][C:10]=3[N:2]([CH3:1])[C:3]2=[O:15])=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 33143973-Methyl-7-propylpurine-2,6-dioneHCID 114492081-[(6-Bromohexyl)oxy]-4-chlorobenzene

Product 1

HCID 14851753HCID 14851753, compoundYield 51%

Procedure

3-Methyl-7-propylxanthine and 6-(4-chlorophenoxy)hexyl bromide were reacted and treated in substantially the same manner as described in Example 9(a) to give 1-[6-(4-chlorophenoxy)hexyl]-3-methyl-7-propylxanthine (51%).

Workup

  1. additiontreated in substantially the same manner

Sources & evidence

ORD record
ord-8a42e3609b2743e788681ae4a837cc8f
Source dataset
uspto-grants-1990_07
Patent number
US04942143

Reaction notes

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