7-Hexyl-3-Methylxanthine → 1-[6-(4-Chlorophenoxy)hexyl]-7-hexyl-3-methylxanthine

HRID 2165820Notes

Reaction equation

HRID 2165820 reaction equation
[CH2:1]([N:7]1[C:15]2[C:14](=[O:16])[NH:13][C:12](=[O:17])[N:11]([CH3:18])[C:10]=2[N:9]=[CH:8]1)[CH2:2][CH2:3][CH2:4][CH2:5][CH3:6].[Cl:19][C:20]1[CH:33]=[CH:32][C:23]([O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30]Br)=[CH:22][CH:21]=1>>[Cl:19][C:20]1[CH:33]=[CH:32][C:23]([O:24][CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][N:13]2[C:14](=[O:16])[C:15]3[N:7]([CH2:1][CH2:2][CH2:3][CH2:4][CH2:5][CH3:6])[CH:8]=[N:9][C:10]=3[N:11]([CH3:18])[C:12]2=[O:17])=[CH:22][CH:21]=1

Participants

3

Reactant 2

HCID 42536707-Hexyl-3-MethylxanthineHCID 114492081-[(6-Bromohexyl)oxy]-4-chlorobenzene

Product 1

HCID 217698421-[6-(4-Chlorophenoxy)hexyl]-7-hexyl-3-methylxanthineYield 84%

Procedure

7-Hexyl-3-methylxanthine and 6-(4-chlorophenoxy)hexyl bromide were reacted and treated in substantially the same manner as described in Example 9(a) to give 1-[6-(4-chlorophenoxy)hexyl]-7-hexyl-3-methylxanthine (84%) as an oil.

Workup

  1. additiontreated in substantially the same manner

Sources & evidence

ORD record
ord-8cb7d1f5b99246219a71e05a0aca59e6
Source dataset
uspto-grants-1990_07
Patent number
US04942143

Reaction notes

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