Acrylic Acid → HCID 14072047, compound

HRID 2165864Notes

Reaction equation

HRID 2165864 reaction equation
[NH2:1][C:2]1[CH:15]=[CH:14][C:5]([C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[O:7])=[CH:4][CH:3]=1.[C:16]([OH:20])(=[O:19])[CH:17]=[CH2:18]>C(O)(=O)C>[C:6]([C:5]1[CH:4]=[CH:3][C:2]([NH:1][CH2:18][CH2:17][C:16]([OH:20])=[O:19])=[CH:15][CH:14]=1)(=[O:7])[C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

Participants

4

Reactant 2

HCID 6581Acrylic AcidHCID 143464-Aminobenzophenone

Product 1

HCID 14072047HCID 14072047, compound

Reagents, catalysts & solvents 1

HCID 176Acetic AcidSolvent

Procedure

1.97 g of 4-aminobenzophenone (0.01 mole) and 1.44 g of acrylic acid (0.02 mole) are dissolved in 10 ml of glacial acetic acid and boiled under reflux for 2 days. The solution is evaporated to dryness in vacuo, and the residue is redissolved in 2 N sodium hydroxide solution, and the solution is extracted several times with diethyl ether. The aqueous solution is adjusted to pH 4-5 with 2 N HCl, and the precipitate is filtered off with suction and washed with water.

Workup

  1. temperatureunder reflux for 2 days
  2. customThe solution is evaporated to dryness in vacuo
  3. dissolutionthe residue is redissolved in 2 N sodium hydroxide solution
  4. extractionthe solution is extracted several times with diethyl ether
  5. filtrationthe precipitate is filtered off with suction
  6. washwashed with water

Sources & evidence

ORD record
ord-49c3a999ce0943f296636c0e9b67fc37
Source dataset
uspto-grants-1990_07
Patent number
US04942176

Reaction notes

Loading…