Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Thiophosgene → 4-Isothiocyanato-1-naphthonitrile
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Thiophosgene | HCID 10040 | — |
| 반응물 | 4-Amino-1-naphthalenecarbonitrile | HCID 42828 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 용매 | Sodium Bicarbonate | HCID 516892 | — |
| 생성물 | 4-Isothiocyanato-1-naphthonitrile | HCID 18316068 | 93.1% |
반응 단계
Thiophosgene (9.1 mL, 118.9 mmol) was added to a stirring slurry of 4-amino-1-naphthalenecarbonitrile (10 g, 59.45 mmol) in dichloromethane (200 mL) and saturated aqueous NaHCO3 solution (200 mL) at 0° C., and the mixture stirred for 3 days at room temp. The layers were separated and the organic layer concentrated to provide 4-isothiocyanato-1-naphthonitrile as a tan solid (11.64 g, 93%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08193234B2 |
| 출처 데이터셋 | uspto-grants-2012_06 |
| ORD ID | ord-ee4c36772a5e4b93900d86847385c95d |
| 출처 메모 | uspto-grants-2012_06 |