HCID 14832882, compound → HCID 14832888, compound

Participants

Reaction Steps

A suspension of 80 mg of Ni[PPh3 ]2Cl2 and 20 ml of ether were added to 1.9 g of Compound 3, and stirred for 15 minutes in a nitrogen atmosphere. 10 mmol of phenylmagnesium bromide were added and refluxed for 4 hours. After cooling down, the solution was quenched with 20 ml of 1N hydrochloric acid and extracted with chloroform. The organic layer was evaporated under reduced pressure, and purified with column chromatography (silica gel, hexane/benzene) to get 670 mg of pure 6,6'-dioctadecyl-3,3'-diphenyl-2,2'-dimethoxy-1,1'-binaphthyl. (yield 36%) (Compound 4).

Provenance & Evidence