Benzylamine → HCID 14277790, compound

HRID 2165999Notes

Reaction equation

HRID 2165999 reaction equation
[CH3:1][C:2]1O[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[C:5]([C:14]([NH:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:15])[C:4](=[O:23])[CH:3]=1.[CH2:24]([NH2:31])[C:25]1C=C[CH:28]=[CH:27][CH:26]=1>C(O)C>[CH3:1][C:2]1[N:31]([CH2:24][CH2:25][CH2:26][CH2:27][CH3:28])[C:6]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)=[C:5]([C:14]([NH:16][C:17]2[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=2)=[O:15])[C:4](=[O:23])[CH:3]=1

Participants

4

Reactant 2

HCID 7504BenzylamineHCID 13854013HCID 13854013, compound

Product 1

HCID 14277790HCID 14277790, compoundYield 57.9%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

1 g (3.23 mmol) of 6-methyl-4-oxo-N,2-diphenyl-4H-pyran-3-carboxamide and 590 mg (6.78 mmol) of benzylamine were dissolved in 10 ml of ethanol, and the resulted mixture was stirred over night at room temperature. Ethanol was removed under vacuo. The crystal residue was recrystallized from ethylacetate to afford 700 mg of the title compound having mp. 164°-165.5° C.

Workup

  1. customEthanol was removed under vacuo
  2. customThe crystal residue was recrystallized from ethylacetate

Sources & evidence

ORD record
ord-20cb2996e8094c86af2cf8fe8fa63482
Source dataset
uspto-grants-1990_07
Patent number
US04943314

Reaction notes

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