Diethyl Ether → HCID 178448014, compound

Participants

Reaction Steps

7.5 mmol of KH and 40 ml of dimethyl carbonate are added to a solution of 2.0 g of 3-[trans-4-(trans-4-n-propylcyclohexyl)-cyclohexyl]-cyclohexanone (Example 1) in 40 ml of THF, and the mixture is boiled for 2 hours. Customary working up (silica gel; 6.5:3:0.5 petroleum ether: methylene chloride:ether) gives methyl 4-[trans-4-(trans-4-n-propylcyclohexyl)-cyclohexyl]-2-oxocyclohexanecarboxylate, which is predominantly in the enol form, m.p. 154°, c.p. 192°.

Provenance & Evidence