Ethyl 3-aminopropanoate → HCID 59225846, compound

HRID 216605Notes

Reaction equation

HRID 216605 reaction equation
[Br:1][C:2]1[N:6]([C:7]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10]([C:17]#[N:18])=[CH:9][CH:8]=2)[C:5]([S:19][CH2:20][C:21](O)=[O:22])=[N:4][CH:3]=1.[CH2:24]([O:26][C:27](=[O:31])[CH2:28][CH2:29][NH2:30])[CH3:25]>>[Br:1][C:2]1[N:6]([C:7]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10]([C:17]#[N:18])=[CH:9][CH:8]=2)[C:5]([S:19][CH2:20][C:21]([NH:30][CH2:29][CH2:28][C:27]([O:26][CH2:24][CH3:25])=[O:31])=[O:22])=[N:4][CH:3]=1

Participants

3

Reactant 2

HCID 419889Ethyl 3-aminopropanoateHCID 461788622-(5-bromo-1-(4-cyanonaphthalen-1-yl)-1H-imidazol-2-ylthio)acetic acid

Product 1

HCID 59225846HCID 59225846, compound

Procedure

Ethyl 3-(2-(5-bromo-1-(4-cyanonaphthalen-1-yl)-1H-imidazol-2-ylthio)acetamido)propanoate was prepared by coupling 2-(5-bromo-1-(4-cyanonaphthalen-1-yl)-1H-imidazol-2-ylthio)-acetic acid with β-alanine ethyl ester according to the procedure described in example 2.

Sources & evidence

ORD record
ord-b31f2c7d9e1c4d92afa4f3a485c78994
Source dataset
uspto-grants-2012_06
Patent number
US08193234B2

Reaction notes

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