Lawesson's reagent → HCID 23042086, compound

HRID 2166093Notes

Reaction equation

HRID 2166093 reaction equation
[F:1][C:2]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:3]=1[C:4]([NH:6][NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[C:14]([F:17])([F:16])[F:15])=O.COC1C=CC(P2(SP(C3C=CC(OC)=CC=3)(=S)S2)=[S:32])=CC=1>>[F:1][C:2]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:3]=1[C:4]([NH:6][NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][C:9]=1[C:14]([F:17])([F:16])[F:15])=[S:32]

Participants

3

Reactant 2

HCID 87949Lawesson's reagentHCID 23042045HCID 23042045, compound

Product 1

HCID 23042086HCID 23042086, compound

Procedure

Analogously to the procedure described in Example 58, by treating 2,6-difluoro-N'-(α,α,α-trifluoro-o-tolyl)-benzhydrazide (see Examples 35 and 36) with Lawesson reagent there is produced 2,6-difluoro-N'-(α,α,α-trifluoro-o-tolyl)-thiobenzhydrazide which is required as the starting material in Example 18.

Sources & evidence

ORD record
ord-afe0b086423548eb96e08cc08374ed9f
Source dataset
uspto-grants-1990_07
Patent number
US04943583

Reaction notes

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