4-Phenoxyphenol → HCID 14280223, compound

Participants

Reaction Conditions

Reaction Steps

At 10° to 20° C., 18.6 g of p-phenoxyphenol in 50 ml of dimethyl sulfoxide is dripped into 3.1 g of sodium hydride (85% strength in paraffin) in 100 ml of dimethyl sulfoxide. The mixture is stirred for 30 minutes at 50° C. and then 3-methyl-5-chloromethylisoxazole is dripped in at 15°-20° C. The mixture is worked up in the usual manner after 8 hours at 70° C. There is obtained 26.7 g of compound no. 31.25 of m.p. 48°-51° C.

Provenance & Evidence