1-Dodecanol → HCID 178443286, compound

Participants

Reaction Conditions

Reaction Steps

A 500 ml round bottom flask equipped with a condenser, thermometer (with controller) and overhead stirrer was charged with 93 g (0.5 moles) of C12H25OH and (0.25 moles) of NaH. The mixture exothermed to 70° C. After the exotherm began to subside, the mixture was heated to 100° C. with stirring. After about two hours, a light grey paste was formed. This paste was subjected to a Kugelrohr distillation at 180° C. The non-volatile residue was 54.6% of the charge (theory for C12H24ONa=53.0%). The hard, dry, white powder residue was recovered. Analysis by titration showed the yield was 96.5% of theory for the named compound.

Provenance & Evidence