Butyl isocyanate → HCID 57238985, compound

HRID 2166330Notes

Reaction equation

HRID 2166330 reaction equation
[CH2:1]([N:5]=[C:6]=[O:7])[CH2:2][CH2:3][CH3:4].[Cl:8][C:9]1[CH:14]=[C:13]([NH2:15])[N:12]=[C:11]([NH2:16])[N:10]=1>CS(C)=O>[NH2:16][C:11]1[N:12]=[C:13]([NH:15][C:6]([NH:5][CH2:1][CH2:2][CH2:3][CH3:4])=[O:7])[CH:14]=[C:9]([Cl:8])[N:10]=1

Participants

4

Reactant 2

HCID 8110Butyl isocyanateHCID 674322,4-Diamino-6-chloropyrimidine

Product 1

HCID 57238985HCID 57238985, compound

Reagents, catalysts & solvents 1

HCID 679Dimethyl SulfoxideSolvent

Conditions

Temperature
80 °C

Procedure

8.6 cm3 of n-butylisocyanate was added to a suspension of 5 g of 4-chloro-2,6-diaminopyrimidine in 50 cm3 of DMSO then heated to 80° C. until the starting compound was shown by TLC to have disappeared.

Sources & evidence

ORD record
ord-24c43a002fe141a0bd2d60eab60a4ce7
Source dataset
uspto-grants-1990_07
Patent number
US04945093

Reaction notes

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