HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenyl-1-propanone → 2-Bromopropiophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenyl-1-propanone | HCID 7148 | — |
| Reactant | Bromine | HCID 24408 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2-Bromopropiophenone | HCID 16452 | — |
Reaction Steps
A solution of 82 g (0.51 mol) of bromine in 100 ml of dichloromethane is added dropwise to a solution of 72 g (0.5 mol) of propiophenone in 500 ml of dichloromethane, at 20° C. After 30 minutes, the solution is evaporated down. 2-Bromopropiophenone is obtained quantitatively, and is directly reacted further.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04945101 |
| Source dataset | uspto-grants-1990_07 |
| ORD ID | ord-af9879f9d2ca409987b05d6dcc52be58 |
| Source note | uspto-grants-1990_07 |