HuagongsheHuagongshe Chemistry Print Report · For research reference only
1,3-Propanediol, 2-methylene- → 3-Hexadecylaminothiocarbonyloxy-2-methylenepropan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1,3-Propanediol, 2-methylene- | HCID 77048 | — |
| Reactant | Hexadecyl isothiocyanate | HCID 138233 | — |
| Catalyst | 4-(Dimethylamino)pyridine | HCID 14284 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | 3-Hexadecylaminothiocarbonyloxy-2-methylenepropan-1-ol | HCID 54063336 | — |
Reaction Steps
Hexadecyl isothiocyanate (9.65 g) and 2-methylenepropane-1,3-diol) (3.0 g) were heated with pyridine (17 ml) and 4-dimethylaminopyridine (0.8 g) to 104° C. for 6.5 hours. The mixture was evaporated to dryness in vacuo and chromatographed on a Waters PrepLC®/System 500A using a PrepPAK®-500/SILICA cartridge with ether/chloroform/hexane 2:2:9 as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04945098 |
| Source dataset | uspto-grants-1990_07 |
| ORD ID | ord-818d377f8cbf4779a998dd70ca11179a |
| Source note | uspto-grants-1990_07 |