Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Pyridine | HCID 1049 | — |
| Reactant | 1,3-Propanediol, 2-methylene- | HCID 77048 | — |
| Reactant | Cetyl chloroformate | HCID 97633 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 23039610 | HCID 23039610 | — |
Reaction Steps
2-Methylenepropane-1,3-diol (5.0 g), hexadecyloxycarbonylchloride (17.4 g) and pyridine (4.4 g) was dissolved in methylene chloride (60 ml). The mixture was stirred for 2.5 hours at 22° C. The mixture was purified through a column of silica gel 60 (70-230 mesh, 30 g), eluting with ether/chloroform 1:1. Further purification was achieved by chromatography on a Waters PrepLC®-System 500A using a PrepPAK®-500-SILICA cartridge with ether/chloroform/pentane 1:1:3 as eluent.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04945098 |
|---|
| Source dataset | uspto-grants-1990_07 |
|---|
| ORD ID | ord-fbf0b50dfed64e1b9b3368cc30c81277 |
|---|
| Source note | uspto-grants-1990_07 |
|---|
