HuagongsheHuagongshe Chemie-Druckbericht · Nur für Forschungszwecke
1,5-Pentanediol, 1,5-dimethanesulfonate → 1-Hexadecyloxy-3-[5-(methanesulfonyloxy)pentyloxy]-2-methylenepropane
Beteiligte Stoffe
| Rolle | Name | HCID | Einwaage |
|---|---|---|---|
| Edukt | 1,5-Pentanediol, 1,5-dimethanesulfonate | HCID 16920 | — |
| Edukt | Sodium hydride | HCID 24758 | — |
| Edukt | 3-Hexadecyloxy-2-methylenepropan-1-ol | HCID 11358886 | — |
| Lösungsmittel | Dimethylformamide | HCID 6228 | — |
| Produkt | 1-Hexadecyloxy-3-[5-(methanesulfonyloxy)pentyloxy]-2-methylenepropane | HCID 23039596 | — |
Reaktionsbedingungen
| Temperatur | 54 °C |
|---|
Reaktionsschritte
3-Hexadecyloxy-2-methylenepropan-1-ol (from Preparation 1) (4.45 g), sodium hydride dispersion (55-60% in oil, 1.4 g), and 1,5-dimethanesulfonyloxypentane (10.9 g) were mixed in dry dimethylformamide (33 ml) and stirred at 54° C. for 20 hours. Following the work-up procedure described in Preparation 7, the desired product was obtained.
Herkunft & Nachweise
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patentnummer | US04945098 |
| Quelldatensatz | uspto-grants-1990_07 |
| ORD ID | ord-c5158f21fbb643de986a729d7be71e49 |
| Quellennotiz | uspto-grants-1990_07 |