Acetic Anhydride → HCID 59189839, compound

Participants

Reaction Steps

Pyridine (4 mL) and acetic anhydride (61 μL, 0.65 mmol) were added to 2-aminocarbonylamino-6-(3-hydroxymethylphenyl)indole-3-carboxamide (Compound 12-1, 0.18 g, 0.55 mmol), and the mixture was stirred at room temperature overnight. The reaction mixture was concentrated under reduced pressure, and water (10 mL) was added to the residue. The precipitated solid was separated by filtration. The resultant solid was washed with water (10 mL) and dried under reduced pressure to give the title compound (0.17 g) as a slightly brown solid (yield 87%).

Provenance & Evidence