8-Bromooctanoic acid → HCID 23039608, compound

HRID 2166430Notes

Reaction equation

HRID 2166430 reaction equation
[CH2:1]([NH:16][C:17]([O:19][CH2:20][C:21](=[CH2:24])[CH2:22][OH:23])=[O:18])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15].[Br:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][C:33](O)=[O:34]>>[CH2:1]([NH:16][C:17]([O:19][CH2:20][C:21](=[CH2:24])[CH2:22][O:23][C:33](=[O:34])[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][CH2:26][Br:25])=[O:18])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH3:15]

Participants

3

Reactant 2

HCID 5482758-Bromooctanoic acidHCID 23039602HCID 23039602, compound

Product 1

HCID 23039608HCID 23039608, compound

Procedure

Following the procedure described in Preparation 9, but replacing 3-octadecylaminocarbonyloxy-2-methylenepropan-1-ol with 3-pentadecylaminocarbonyloxy-2-methylenepropan-1-ol (from Preparation 4), and replacing 6-bromohexanoic acid with 8-bromooctanoic acid, the desired product was obtained.

Workup

  1. customdescribed in Preparation 9

Sources & evidence

ORD record
ord-232bdc666ebc4df99fe6bd3e2cbf833b
Source dataset
uspto-grants-1990_07
Patent number
US04945098

Reaction notes

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