HRID2166437

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID20210

6-Bromohexanoic acid

C6H11BrO2

HCID548275

8-Bromooctanoic acid

C8H15BrO2

结构：CCCCCCCCCCCCCCCCCCNC(=O)OCC(CO)=C(C)C

HCID23039642

未命名化合物

PRODUCTS

生成物

结构：CCCCCCCCCCCCCCCCCCNC(=O)OCC(COC(=O)CCCCCCCBr)=C(C)C

HCID23039609

未命名化合物

PROCEDURE

实验过程

Following the procedure described in Preparation 9, but replacing 3-octadecylaminocarbonyloxy-2-methylenepropan-1-ol with 3-octadecylaminocarbonyloxy-2-isopropylidenepropan-1-ol (from Preparation 26) and 6-bromohexanoic acid with 8-bromooctanoic acid, the desired product was obtained.

WORKUP

后处理

customdescribed in Preparation 9

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-442049124cc54d3b87f418b119c25557
来源数据集: uspto-grants-1990_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04945098
来源说明: uspto-grants-1990_07

反应 SMILES

[CH2:1]([NH:19][C:20]([O:22][CH2:23][C:24](=[C:27]([CH3:29])[CH3:28])[CH2:25][OH:26])=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].BrCCCCCC(O)=O.[Br:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][C:47](O)=[O:48]>>[CH2:1]([NH:19][C:20]([O:22][CH2:23][C:24](=[C:27]([CH3:28])[CH3:29])[CH2:25][O:26][C:47](=[O:48])[CH2:46][CH2:45][CH2:44][CH2:43][CH2:42][CH2:41][CH2:40][Br:39])=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]