HRID2166450

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID1146

Trimethylamine

C3H9N

结构：C=C(COC(=O)CCCCCBr)COC(=O)NCCCCCCCCCCCCCCCCCC

HCID14064645

未命名化合物

PRODUCTS

生成物

结构：C=C(COC(=O)CCCCC[N+](C)(C)C)COC(=O)NCCCCCCCCCCCCCCCCCC.[Br-]

HCID23039637

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID702

Ethanol

C2H6O

CONDITIONS

反应条件

温度: 60 °C

PROCEDURE

实验过程

1-Octadecylaminocarbonyloxy-3-(6-bromohexanoyloxy)-2-methylenepropane (from Preparation 9) (0.84 g) was dissolved in 33% trimethylamine in ethanol (30 ml) and heated to 60° C. in a sealed flask for 5 hours. Excess trimethylamine and ethanol were removed in vacuo.

WORKUP

后处理

customExcess trimethylamine and ethanol were removed in vacuo

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-60dcf8d7720043bd8b5d5745dca2b724
来源数据集: uspto-grants-1990_07
DOI: 10.6084/m9.figshare.5104873.v1
专利: US04945098
来源说明: uspto-grants-1990_07

反应 SMILES

[CH2:1]([NH:19][C:20]([O:22][CH2:23][C:24](=[CH2:35])[CH2:25][O:26][C:27](=[O:34])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][Br:33])=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:36][N:37]([CH3:39])[CH3:38]>C(O)C>[Br-:33].[CH2:1]([NH:19][C:20]([O:22][CH2:23][C:24](=[CH2:35])[CH2:25][O:26][C:27](=[O:34])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][N+:37]([CH3:39])([CH3:38])[CH3:36])=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]