1-Octadecylaminocarbonyloxy-3-(6-bromohexanoyloxy)-2-methylenepropane → HCID 67936705, compound

HRID 2166451Notes

Reaction equation

HRID 2166451 reaction equation
[CH2:1]([NH:19][C:20](OCC(=C)COC(=O)CCCCC[Br:33])=O)[CH2:2][CH2:3][CH2:4]CCCCCCCCCCCCCC.[CH2:36]([NH:54][C:55]([O:57][CH2:58][C:59](=[CH:70][CH3:71])[CH2:60][O:61][C:62](=[O:69])[CH2:63][CH2:64][CH2:65][CH2:66][CH2:67]Br)=[O:56])[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH3:53]>>[Br-:33].[CH2:36]([NH:54][C:55]([O:57][CH2:58][C:59](=[CH:70][CH3:71])[CH2:60][O:61][C:62](=[O:69])[CH2:63][CH2:64][CH2:65][CH2:66][CH2:67][N+:19]1[CH:1]=[CH:2][CH:3]=[CH:4][CH:20]=1)=[O:56])[CH2:37][CH2:38][CH2:39][CH2:40][CH2:41][CH2:42][CH2:43][CH2:44][CH2:45][CH2:46][CH2:47][CH2:48][CH2:49][CH2:50][CH2:51][CH2:52][CH3:53]

Participants

3

Reactant 2

HCID 140646451-Octadecylaminocarbonyloxy-3-(6-bromohexanoyloxy)-2-methylenepropaneHCID 53924098HCID 53924098, compound

Product 1

HCID 67936705HCID 67936705, compound

Procedure

Following the procedure described in Example 6, but replacing 1-octadecylaminocarbonyloxy-3-(6-bromohexanoyloxy)-2-methylenepropane with an approx. 1:1 mixture of E- and Z-isomers of 1-octadecylaminocarbonyloxy-3-(6-bromohexanoyloxy)-2-ethylidenepropane (from Preparation 29), an approx. 1:1 mixture of E- and Z-isomers of the desired compound is obtained.

Sources & evidence

ORD record
ord-f75370d3231f4702857dba9623f123db
Source dataset
uspto-grants-1990_07
Patent number
US04945098

Reaction notes

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