Methyl iodide → HCID 178459551, compound

HRID 2166453Notes

Reaction equation

[CH2:1]([NH:19][C:20]([O:22][CH2:23][C:24](=[CH2:41])[CH2:25][O:26][C:27](=[O:40])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][N:35]1[CH:39]=[CH:38][N:37]=[CH:36]1)=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18].[CH3:42][I:43]>C(Cl)(Cl)Cl>[I-:43].[CH2:1]([NH:19][C:20]([O:22][CH2:23][C:24](=[CH2:41])[CH2:25][O:26][C:27](=[O:40])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][N+:35]1[CH:39]=[CH:38][N:37]([CH3:42])[CH:36]=1)=[O:21])[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH3:18]

Participants

Conditions

Temperature: 22 °C

Procedure

1-Octadecylaminocarbonyloxy-3-[8-(1-imidazolyl)octanoyloxy]-2-methylenepropane (from Preparation 33) (0.55 g) was dissolved in chloroform (10 ml). Methyl iodide (6 ml) was added, and the mixture stirred at 22° C. for 24 hours. The mixture was evaporated to dryness in vacuo to give the desired product.

Workup

customThe mixture was evaporated to dryness in vacuo

Sources & evidence

ORD record: ord-8e8830f228284eba9940de9839c77836
Source dataset: uspto-grants-1990_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04945098

Reaction notes

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