L-Aspartic Acid → N-[(3S)-Tetrahydro-2,5-dioxo-3-furanyl]formamide

HRID 2166471Notes

Reaction equation

HRID 2166471 reaction equation
[NH2:1][C@H:2]([C:7]([OH:9])=[O:8])[CH2:3][C:4]([OH:6])=O.[C:10](OC(=O)C)(=[O:12])C>C(O)=O>[CH:10]([NH:1][C@@H:2]1[C:7](=[O:8])[O:9][C:4](=[O:6])[CH2:3]1)=[O:12]

Participants

4

Reactant 2

HCID 5960L-Aspartic AcidHCID 7918Acetic Anhydride

Product 1

HCID 11298025N-[(3S)-Tetrahydro-2,5-dioxo-3-furanyl]formamide

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

reacting L-aspartic acid with formic acid in the presence of an effective amount of acetic anhydride under conditions sufficient to form N-formyl-L-aspartic anhydride;

Sources & evidence

ORD record
ord-a3febab9241b42f08bbfd5c0f22ed7d9
Source dataset
uspto-grants-1990_07
Patent number
US04945172

Reaction notes

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