HCID 13055757, compound → HCID 13055758, compound

Participants

Reaction Steps

A solution of 14.6 g (64 mmol) of the product of Step A in 700 ml of chloroform was vigorously stirred while 60 g of activated manganese dioxide were added thereto and the mixture was then stirred at room temperature for 28 hours. The mixture was filtered and the filter was throughly washed with chloroform. The filtrate was evaporated to dryness under reduced pressure and the residue was crystallized from ethyl acetate to obtain 10.9 g (75% yield) of 5-methoxyimidazo[1,2-a]quinolin-2-carboxaldehyde in the form of a white crystalline solid melting at 195°-196° C.

Provenance & Evidence