Sodium Bicarbonate → HCID 178466163, compound

Participants

Reaction Steps

4.8 g of α-chloro-α-(3,4-diethoxyphenyl)acetonitrile and 2.3 g of thiourea, in 70 ml of ethanol, are stirred under reflux for 1 hour. After cooling, the solution is poured in 200 ml of water, neutralized with a saturated aqueous solution of sodium hydrogen carbonate and extracted with chloroform. The extract is washed with water, dried (MgSO4) and distilled to remove the chloroform. The above procedure provides 3.9 g (69.6%) of 5-(3,4-diethoxyphenyl)-2,4-diiminothiazolidine, m.p. 185°-190° C.

Provenance & Evidence