Potassium Sodium Tartrate → HCID 13062052, compound

Participants

Reaction Steps

The crude product of Example 10 (1.36 g) in dry ether (25 cm3) was added dropwise to a stirred, refluxing suspension of lithium aluminium hydride (0.45 g) in dry ether (10 cm3). The mixture was heated to reflux for 6 hr. and was then allowed to cool. Saturated Rochelle salt solution (50 cm3) was added and the mixture was stirred to dissolve aluminium salts. The phases were separated and the aqueous phase was extracted with further ether. The extracts were dried (Na2SO4) and evaporated, leaving the title product as an oil (1.27 g). The crude title base (1.1 g) was converted in ethyl acetate to its hydrogen oxalate salt, which was recrystallised from ethyl acetate-methanol giving crystals (0.73 g), m.p. 213°-5° (decomp.).

Provenance & Evidence