Sodium Bicarbonate → HCID 20499800, compound

Participants

Reaction Steps

A solution of 1-benzyl-1,6-dihydro-5-(p-tolyl)-3-[2H]-pyridone hydrochloride hydrate (4.7 g) in ethanol (100 ml) was treated with sodium bicarbonate (1.2 g), followed by sodium borohydridge (1 g). After 1 hour the solvents were removed under reduced pressure and the residue partitioned between water (50 ml) and ether (200 ml). The ether layer was dried and the solvent removed under reduced pressure to give the title compound as an oil (3.5 g).

Provenance & Evidence