Potassium Hydroxide → HCID 23695813, compound

HRID 2166611Notes

Reaction equation

HRID 2166611 reaction equation
[C:1]1([NH:7][C:8](=[O:17])[CH:9]2[O:16][CH:10]2[C:11]([O:13]CC)=[O:12])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[OH-].[K+:19]>C(O)C>[C:1]1([NH:7][C:8](=[O:17])[CH:9]2[O:16][CH:10]2[C:11]([O-:13])=[O:12])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1.[K+:19]

Participants

4

Reactant 2

HCID 14797Potassium HydroxideHCID 13150800HCID 13150800, compound

Product 1

HCID 23695813HCID 23695813, compoundYield 74.6%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent2×

Procedure

Ethyl N-phenyl-2,3-epoxysuccinamate (Compound No. 1) (0.9 g) was dissolved in ethyl alcohol (30 ml) and an ethyl alcohol solution (5 ml) containing KOH (0.27 g) was added to the solution under ice-cooling, followed by stirring for an hour. The precipitate produced was collected on a filter and recrystallized from a mixture of ethyl alcohol-water to give 0.7 g of potassium N-phenyl-2,3-epoxysuccinamate (Compound No. 95) as colorless powder melting over 300° C. (decomposition).

Workup

  1. additionwas added to the solution under ice-
  2. temperaturecooling
  3. customThe precipitate produced
  4. customwas collected on
  5. filtrationa filter
  6. customrecrystallized from a mixture of ethyl alcohol-water

Sources & evidence

ORD record
ord-49d2aea6a8a8410a86f3569ff96022a1
Source dataset
uspto-grants-1983_06
Patent number
US04387238

Reaction notes

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