HCID 53734901, compound → HCID 53734900, compound

HRID 2166680Notes

Reaction equation

HRID 2166680 reaction equation
[CH2:1]([O:3][C:4]([O:6][C@@H:7]1[C@@:32]2([CH3:33])[C:11](=[CH:12][CH:13]=[C:14]3[C@@H:31]2[CH2:30][CH2:29][C@@:28]2([CH3:34])[C@H:15]3[CH2:16][CH2:17][C@@H:18]2[C@H:19]([CH3:27])[CH2:20][CH2:21][CH2:22][C:23]([OH:26])([CH3:25])[CH3:24])[CH2:10][C@@H:9]([O:35][C:36]([O:38][CH2:39][CH3:40])=[O:37])[CH2:8]1)=[O:5])[CH3:2].C(OC(O[C@@H]1[C@@]2(C)C(C=C[C@@H]3[C@@H]2CC[C@@]2(C)[C@H]3CC[C@@H]2[C@H](C)CCCC(O)(C)C)=C[C@@H](OC(OCC)=O)C1)=O)C>CCOCC>[CH2:1]([O:3][C:4]([O:6][CH:7]1[C@@:32]2([CH3:33])[C:11](=[CH:12][CH:13]=[C:14]3[C@@H:31]2[CH2:30][CH2:29][C@@:28]2([CH3:34])[C@H:15]3[CH2:16][CH2:17][C@@H:18]2[C@H:19]([CH3:27])[CH2:20][CH2:21][CH2:22][C:23]([OH:26])([CH3:25])[CH3:24])[CH2:10][CH:9]([O:35][C:36]([O:38][CH2:39][CH3:40])=[O:37])[CH2:8]1)=[O:5])[CH3:2]

Participants

4

Reactant 2

HCID 53734901HCID 53734901, compound2×HCID 54541820HCID 54541820, compound

Product 1

HCID 53734900HCID 53734900, compound

Reagents, catalysts & solvents 1

HCID 3283Diethyl EtherSolvent

Procedure

The product (482 g) obtained in (1) above was dissolved in ether (10 l). The resulting solution was subjected to the measurement of UV spectrum with a spectrophotometer (cell length; 1 cm, wavelength; 340 nm-200 nm). The UV spectrum showed, as maximum absorbance (λmax), 293, 281, 271, 260 (shoulder), 249.5 (shoulder), 241 and 232. From the ratio of absorbance in λmax ; 281 and 240, the ratio (Δ5,7/Δ4,6) of 1α,3β-diethoxycarbonyloxy-25-hydroxycholesta-5,7-diene to 1α,3β-diethoxycarbonyloxy-25-hydroxycholesta-4,6-diene was 4.36.

Sources & evidence

ORD record
ord-a15e5a2335a84f9190e05c83e64f4dd2
Source dataset
uspto-grants-1983_06
Patent number
US04388243

Reaction notes

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