HCID 13118187, compound → HCID 131713009, compound

HRID 2166687Notes

Reaction equation

HRID 2166687 reaction equation
[C:1]([C:4]1[CH:15]=[CH:14][C:7]([O:8]NCC(O)C)=[CH:6][CH:5]=1)(=[O:3])[CH3:2].[OH:16][CH:17]([CH2:38]OC1C2C(=CC=CC=2)C=CC=1)[CH2:18][NH:19][C:20]1[C:21]2[N:22]=[CH:23][N:24]([C:34]=2[N:35]=[CH:36][N:37]=1)[C@@H:25]1[O:33][C@H:30]([CH2:31][OH:32])[C@@H:28]([OH:29])[C@H:26]1[OH:27]>>[C:1]([C:4]1[CH:5]=[CH:6][C:7]([O:8][CH2:38][CH:17]([OH:16])[CH2:18][NH:19][C:20]2[C:21]3[N:22]=[CH:23][N:24]([C:34]=3[N:35]=[CH:36][N:37]=2)[C@@H:25]2[O:33][C@H:30]([CH2:31][OH:32])[C@@H:28]([OH:29])[C@H:26]2[OH:27])=[CH:14][CH:15]=1)(=[O:3])[CH3:2]

Participants

3

Reactant 2

HCID 13118187HCID 13118187, compoundHCID 20498462HCID 20498462, compound

Product 1

HCID 131713009HCID 131713009, compound

Procedure

By substituting (4-acetylphenoxy)-2-hydroxypropylamine (3.65 g, 0.017 mole) for the 2-hydroxy-(1-naphthalenyloxy)propylamine of Example 1 and following the method of Example 1, N6 -[3-(4-acetylphenoxy)-2-hydroxypropyl]-adenosine was obtained.

Sources & evidence

ORD record
ord-b3e9163772a541888afd28089d742061
Source dataset
uspto-grants-1983_06
Patent number
US04388308

Reaction notes

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