HCID 16642394, compound → HCID 178521293, compound
Reaction equation
[C:1]1([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[O:7][CH2:8][CH:9]([OH:12])[CH2:10][NH2:11].OC(COC1C2C(=CC=CC=2)C=CC=1)CN[C:23]1[N:31]=[CH:30][N:29]=[C:28]2[C:24]=1[N:25]=[CH:26][NH:27]2>>[C:1]1([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[O:7][CH2:8][CH:9]([OH:12])[CH2:10][NH:11][C:23]1[N:31]=[CH:30][N:29]=[C:28]2[C:24]=1[N:25]=[CH:26][NH:27]2Participants
3
Procedure
By substituting 3-[(1,1'-biphenyl)-2-yloxy]-2-hydroxypropylamine (4.88 g, 0.0174 moles) for the starting material of Example 2 and following the method of Example 2, the desired compound is obtained.
Sources & evidence
- ORD record
- ord-01d9e6272e0a458e9c006b86bb73b0e2
- Source dataset
- uspto-grants-1983_06
- Patent number
- US04388308
Reaction notes
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