5-(((2-Aminoethyl)thio)methyl)-N,N-dimethyl-2-furanmethanamine → HCID 13137355, compound

Participants

Reaction Steps

A mixture of 2-(5-dimethylaminomethyl-2-furanylmethylthio)ethylamine (1.64 g) and 2-nitroamino-5-(5-dimethylaminomethyl-2-thienylmethyl)-4-pyrimidone (2.01 g) in ethanol (10 ml) was heated under reflux for 30 hr. The ethanol was evaporated in vacuo to yield 2-[2-(5-dimethylaminomethyl-2-furanylmethylthio)ethylamino]-5-(5-dimethylaminomethyl-2-thienylmethyl)-4-pyrimidone as a brown oil which was washed with hot water by decantation. The residue was dissolved in isopropanol and an excess of ethanolic hydrochloric acid was added to the solution.

Provenance & Evidence