反应详情

A mixture of diethylsulphate (57.41 g) and tri-n-propylamine was added dropwise with stirring to a solution of furanylacrylic acid (34.53 g) in acetone (150 ml). When the addition was complete the mixture was refluxed for six hours. The acetone was evaporated at reduced pressure. The resultant oily residue was dissolved in ethyl acetate, washed with aqueous sodium bicarbonate solution dried (MgSO4) and the solvent evaporated to yield ethyl 3-(2-furanyl)acrylate (46.7 g) as a brown oil.

1. additionwas added dropwise
2. additionWhen the addition
3. temperaturewas refluxed for six hours
4. customThe acetone was evaporated at reduced pressure
5. dissolutionThe resultant oily residue was dissolved in ethyl acetate
6. washwashed with aqueous sodium bicarbonate solution
7. dry with materialdried (MgSO4)
8. customthe solvent evaporated