Trifluoroacetic acid → HCID 22823408, compound

Participants

Reaction Steps

The product of Example I, above, (191.5 mg, 0.43 mmol) was dissolved at room temperature in 2 mL of trifluoroacetic acid. After 2 hr, the excess trifluoroacetic acid was removed at 1.6 kPa and room temperature, and the residue was dried at 0.1 Pa overnight. The yield of pale yellow glass was quantitative. It was purified by dissolving in 1 mL of methanol and reprecipitating by adding 30 mL of ether; mp=155.6°; NMR (2/1 CDCl3 /CD3OD) δ(LeuCH3)=1.02 D (6), J=5 Hz, δ(LeuCH2)=1.87 D (2), δ(LeuCH)=4.2 M (1), δ(ArH)=7.6 M (9).

Provenance & Evidence