3-Chloro-2-methylpropyl(dimethyl)ammonium chloride → 1-[2-Chloro-4-(3-dimethylamino-2-methylpropoxy)phenyl]-1-butanone

HRID 2166867Notes

Reaction equation

HRID 2166867 reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([O:8]CCN(CC)CC)[CH:5]=[CH:4][C:3]=1[C:16](=[O:20])[CH2:17][CH2:18][CH3:19].Cl.[CH3:22][N:23]([CH3:29])[CH2:24][CH:25]([CH3:28])[CH2:26]Cl>>[Cl:1][C:2]1[CH:7]=[C:6]([O:8][CH2:26][CH:25]([CH3:28])[CH2:24][N:23]([CH3:29])[CH3:22])[CH:5]=[CH:4][C:3]=1[C:16](=[O:20])[CH2:17][CH2:18][CH3:19]

Participants

3

Reactant 2

HCID 30838413-Chloro-2-methylpropyl(dimethyl)ammonium chlorideHCID 130523711-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-1-butanone

Product 1

HCID 204971671-[2-Chloro-4-(3-dimethylamino-2-methylpropoxy)phenyl]-1-butanone

Procedure

This compound is prepared by essentially the same procedure as described in Example 1 Step A except that the 2-diethylaminoethyl chloride hydrochloride of Example 1 Step A is replaced by an equimolecular quantity of 3-dimethylamino-2-methylpropyl chloride hydrochloride. The product is obtained as a colorless oil upon distillation in vacuo (0.3 mm.).

Workup

  1. customThis compound is prepared by essentially the same procedure
  2. customThe product is obtained as a colorless oil upon distillation in vacuo (0.3 mm.)

Sources & evidence

ORD record
ord-a74bd1e06cf144bda473eb2c21d6dbf9
Source dataset
uspto-grants-1983_06
Patent number
US04390537

Reaction notes

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