1-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-2-methylene-1-butanone → 1-[2-Chloro-4-(3-dimethylamino-2-methylpropoxy)phenyl]-2-methylene-1-butanone

HRID 2166868Notes

Reaction equation

HRID 2166868 reaction equation
Cl[C:2]1C=C(OCCN(CC)CC)C=CC=1C(=O)C(=C)CC.[Cl:22][C:23]1[CH:28]=[C:27]([O:29][CH2:30][CH:31]([CH3:36])[CH2:32][N:33]([CH3:35])[CH3:34])[CH:26]=[CH:25][C:24]=1[C:37](=[O:41])[CH2:38][CH2:39][CH3:40]>>[Cl:22][C:23]1[CH:28]=[C:27]([O:29][CH2:30][CH:31]([CH3:36])[CH2:32][N:33]([CH3:34])[CH3:35])[CH:26]=[CH:25][C:24]=1[C:37](=[O:41])[C:38](=[CH2:2])[CH2:39][CH3:40]

Participants

3

Reactant 2

HCID 130523721-[2-Chloro-4-(2-diethylaminoethoxy)phenyl]-2-methylene-1-butanoneHCID 204971671-[2-Chloro-4-(3-dimethylamino-2-methylpropoxy)phenyl]-1-butanone

Product 1

HCID 130523771-[2-Chloro-4-(3-dimethylamino-2-methylpropoxy)phenyl]-2-methylene-1-butanone

Procedure

This compound is prepared by essentially the same procedure as described in Example 1 Step B except that the 2-chloro-4-(2-diethylaminoethoxy)butyrophenone of Example 1 Step B is replaced by an equimolecular quantity of 1-[2-chloro-4-(3-dimethylamino-2-methylpropoxy)phenyl]-1-butanone. The product is obtained as a yellow oil upon distillation in vacuo (0.3 mm.).

Workup

  1. customThis compound is prepared by essentially the same procedure
  2. customThe product is obtained as a yellow oil upon distillation in vacuo (0.3 mm.)

Sources & evidence

ORD record
ord-4761c9bf7a9641d58a71d765c0e393cb
Source dataset
uspto-grants-1983_06
Patent number
US04390537

Reaction notes

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