反应详情

1 g of the product of Step A was added to a mixture of 20 ml of ethanol and 20 ml of aqueous 2 N sodium hydroxide solution and the mixture was refluxed for 17 hours and was cooled and poured into water. The mixture was extracted with methylene chloride and the organic phase was evaporated to dryness to obtain 4-p-tolylsulfonyl-4-methyl-3-dimethoxymethyl-pentanoic acid.

1. temperaturethe mixture was refluxed for 17 hours
2. temperaturewas cooled
3. extractionThe mixture was extracted with methylene chloride
4. customthe organic phase was evaporated to dryness